pentobarbital will lessen the extent or impact of pimozide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.

pentobarbital will decrease the level or influence of estrogens conjugated synthetic by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will lessen the level or result of nelfinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Contraindicated (1)pentobarbital will lessen the extent or impact of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with strong CYP3A4 inducers will not be advisable

pentobarbital will reduce the extent or impact of fesoterodine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will minimize the extent or outcome of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital will reduce the extent or result of loratadine by influencing hepatic/intestinal enzyme CYP3A4 more info metabolism. Use Warning/Observe.

pentobarbital will minimize the extent or influence of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

In the event the buprenorphine dose is insufficient and also the CYP3A4 inducer cannot be minimized or discontinued, changeover the affected person again into a buprenorphine formulation that permits dose changes.

pentobarbital will lessen the extent or result of irinotecan liposomal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

Watch Intently (1)pentobarbital will increase the stage or result of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will minimize the level or impact of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of fentanyl with CYP3A4 inducers may lead to the lessen in fentanyl plasma concentrations, insufficient efficacy or, quite possibly, development of the withdrawal syndrome within a affected person who may have formulated Actual physical dependence to fentanyl.

pentobarbital will reduce the extent or outcome of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital decreases levels of toremifene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers improve charge of toremifene metabolism, decreasing the continuous-state concentration in serum.